Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study

Abstract Background Blood glucose variability is associated with poor prognosis after cardiac surgery, but the relationship between and postoperative delirium in patients acute aortic dissection unclear. The study aims to investigate association of blood patients. Methods We prospectively analyzed 257 including 103 delirium. were divided into two groups according whether was present. outcome measures delirium, length Intensive Care Unit stay, duration hospital stay. Multivariable Cox competing risk survival models used assess. Results A total subjects enrolled, There statistically significant differences body mass index, history first admission glucose, white cell counts, Acute Physiology Chronic Health Evaluation II score, hypoxemia, mechanical ventilation duration, stay( P < 0.05). group exhibited significantly higher values mean (MBG) standard deviation (SDBG) than non-delirium group( In model 1, adjusted hazard ratio (AHR) 1.436( Model 2, (AHR = 1.418, 95%CI 1.195–1.681, 0.05) remained adjusting for confounders. area under curve SDBG 0.763(95%CI 0.704–0.821, 0.01). sensitivity 81.6%, specificity 57.8%. Conclusions Glucose high glycemic increases